Front. Med. Frontiers in Medicine Front. Med. 2296-858X Frontiers Media S.A. 10.3389/fmed.2022.969122 Medicine Original Research Benefits of a 3-month cycle of weekly virtual museum tours in community dwelling older adults: Results of a randomized controlled trial Beauchet Olivier 1 2 3 4 * Matskiv Jacqueline 2 Galery Kevin 2 Goossens Linda 5 Lafontaine Constance 6 Sawchuk Kim 6 1Departments of Medicine and Geriatrics, University of Montreal, Montreal QC, Canada 2Research Center of the Geriatric University Institute of Montreal, Montreal QC, Canada 3Division of Geriatric Medicine, Department of Medicine, Sir Mortimer B. Davis Jewish General Hospital and Lady Davis Institute for Medical Research, McGill University, Montreal QC, Canada 4Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore 5Education and Wellness Department of the Montreal Museum of Fine Arts, Montreal, QC, Canada 6Faculty of Arts and Science, Concordia University, Montreal, QC, Canada

Edited by: Giovanni Maga, National Research Council (CNR), Italy

Reviewed by: Lina Ma, Capital Medical University, China; Pınar Soysal, Bezmiâlem Vakif Üniversitesi, Turkey

*Correspondence: Olivier Beauchet olivier.beauchet@umontreal.ca

This article was submitted to Geriatric Medicine, a section of the journal Frontiers in Medicine

16 08 2022 2022 9 969122 14 06 2022 14 07 2022 Copyright © 2022 Beauchet, Matskiv, Galery, Goossens, Lafontaine and Sawchuk. 2022 Beauchet, Matskiv, Galery, Goossens, Lafontaine and Sawchuk

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

Background

Museums can be instrumental in fostering social inclusion and may improve the overall health of the older population. Over the course of the 2019 coronavirus pandemic, many older adults suffered as a result of confinement measures, which may have accelerated the processes that lead to physical frailty and increased mental health risks. This study aims to examine whether a 3-month cycle of weekly virtual tours of the Montreal Museum of Fine Arts (MMFA) may have improved feelings of social inclusion, wellbeing and quality of life, and reduced physical frailty in older adults living within the community of Montreal.

Methods and design

A total of 106 older adults, who were community-dwellers living in Montreal (Quebec, Canada), were recruited for a randomized controlled trial in two parallel groups (intervention with n = 53 vs control with n = 53) between January and April 2022. The intervention consisted of a 3-month cycle of weekly virtual museum tours of the MMFA. Social isolation, wellbeing, quality of life and frailty were evaluated using validated scales that were assessed on a web platform at baseline (M0) and after 3 months (M3) in the intervention group. The control group completed the same assessment according to the same schedule. The outcomes were the mean scores at M0 and M3, and changes in mean scores between M0 and M3.

Results

The intervention group showed significant improvements in their social isolation, wellbeing, quality of life and frailty scores when compared to the control group, the highest benefits being observed with frailty.

Conclusion

The results suggest that the 3-month cycle of weekly virtual MMFA tours may improve social inclusion, physical and mental health in community-dwelling older adults living in Montreal.

Trial registration

https://clinicaltrials.gov/ct2/show/NCT05046288, identifier NCT05046288.

older adults social isolation art museum wellbeing quality of life frailty 281107 Fonds de Recherche du Québec-Société et Culture10.13039/100008240

香京julia种子在线播放

    1. <form id=HxFbUHhlv><nobr id=HxFbUHhlv></nobr></form>
      <address id=HxFbUHhlv><nobr id=HxFbUHhlv><nobr id=HxFbUHhlv></nobr></nobr></address>

      Background

      Over the past 2 years of the coronavirus disease 2019 (COVID-19) pandemic (1), physical distancing was deployed as a preventive public health measure to reduce the transmission of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This physical distancing had at least two unintended consequences for older adults. First, these measures often deprived older people of face-to-face access to social activities and social networks, which often led to an increase in their social isolation (2). Second, in many countries, such as Canada, there was an increased demand for access to the health care system and community resources, which could not always be met (3, 4). This combination of an increase in social isolation and increased pressure on the healthcare system and community organizations often led to a degradation in physical and mental health, making older adults frail and increasing their risk of adverse outcomes (5). For instance, research suggests that older adults who experience social isolation are at a greater risk for incident morbidities, which can contribute to greater physical frailty and even premature death (5, 6). Conversely, physical frailty itself may also increase social isolation (5). Moreover, it has been demonstrated that older adults' wellbeing and quality of life are impacted negatively by both social isolation and physical frailty (58). This highlights the need for innovative interventions that promote the social inclusion of older adults, especially in the wake of 2 years of the COVID-19 pandemic.

      Systematic reviews of quantitative studies have attempted to evaluate the effectiveness of interventions designed to increase the social inclusion, and sense of connectedness, of older adults experiencing social isolation (815). Due to the heterogeneity of interventions and their results, to date, there has been no conclusive evidence on the effectiveness of specific strategies to increase social inclusion in this population.

      Further research is required to determine what “works” to improve social inclusion. These systematic reviews do, however, point to three key characteristics of effective interventions. First, group activities have a greater effect than those performed alone (812). Second, engaging participants in goal-oriented endeavors, rather than in passive activities with no explicit purpose, appears to be more effective in increasing feelings of social inclusion (1215). Third, activities that include a creative component (such as arts-based activities) evoke positive emotions that are beneficial (15). Moreover, cultural interventions predicated on any type of arts-based activity have been shown to have beneficial effects that may improve people's quality of life (16, 17).

      A socially-inclusive society enables all to remain engaged in collective daily life for as long as possible as they age (18). The concept of social inclusion implies on-going, meaningful participation in society. Providing occasions and places where individuals may participate in shared activities are key attributes of an inclusive society. Because they offer a variety of opportunities to participate meaningfully in arts-based group activities - from guided tours to lectures and workshops - museums may fulfill such a role, fostering a sense of social inclusion. Indeed, the potential of museums to improve the social inclusion of older adults experiencing social isolation has been demonstrated in a British study on “museums as spaces for wellbeing.”1 Since 2015, a participatory, arts-based workshop series has been offered by the Montreal Museum of Fine Arts (MMFA, Montreal, Quebec, Canada) (19). In an examination of this program, it was demonstrated that an intervention involving art creation in a group setting at the MMFA improved the wellbeing, quality of life and health condition of community-dwelling older adults in Montreal (19). Building on this initial study, in 2019, we then co-developed an arts-based activity with the MMFA, consisting of weekly guided tours carried out over a 3-month cycle. Because of physical distancing requirements during the COVID-19 pandemic, these guided tours were adapted into virtual guided tours. The impacts and effects of such virtual tours on older adults experiencing social isolation had never been examined. We hypothesized that weekly virtual MMFA tours could reduce social isolation and improve the wellbeing, quality of life and health condition, including the physical frailty, of older adults living in Montreal. This study thus aims to examine whether a 3-month cycle of weekly virtual tours of the MMFA may have improved feelings of social inclusion, wellbeing and quality of life, and reduced physical frailty in older adults living within the community of Montreal.

      Methods Design

      The study was a uni-center (Center Intégré Universitaire de Santé et des Services Sociaux du Center-Sud-de-l'ile-de-Montréal, Quebec, Canada) randomized controlled trial (RCT) in two parallel groups (i.e., intervention group, which participated in virtual MMFA tours vs control group, which did not participate in virtual MMFA tours). The control group participants were asked to avoid participation in any arts-based activity 3 months ahead of the study and over the 3-month period of the study itself. Participants were aware of the intervention, and therefore not “blinded” due to the nature of the intervention, which required their explicit commitment to a 3-month cycle of weekly virtual MMFA tours. All staff members of the research team involved in the RCT phases (i.e., recruitment, assessment, and follow-up) were blinded to the allocation of intervention, except one staff member who was responsible for the randomization list. Participants were randomly allocated into intervention and control groups by block randomization with block sizes of 1:1. Randomization lists were established using the N'Query randomization software. This RCT is registered on the ClinicalTrials.gov website (project number NCT05046288) and followed the CONSORT guidelines for RCTs (20).

      Population

      A total of 106 participants were enrolled and completed the full study between January and April of 2022. The inclusion criteria were as follows: aged 65 and over with a life expectancy over 6 months (according to a free software that incorporates socio-demographic, cardio-vascular risk factors, physical activity and income characteristics)2, experiencing social isolation as defined by the 11-item Duke Social Support Index (DSSI) score ≤ 28/33 (see footnote 1), living at home in the urban area of Montreal (Quebec, Canada), able to communicate and write in the language of the recruitment center (i.e., French, English or Chinese) and able to consent to participate in the study. The participants were screened using information provided by community associations in Montreal. They were informed that a clinical study on the effects of weekly virtual MMFA tours on social inclusion, wellbeing, quality of life and health condition was launched by the MMFA in partnership with the Research Center of the Geriatric University Institute of Montreal (CRIUGM; Montreal, Quebec, Canada) and that the MMFA and CRIUGM were recruiting participants. Potential participants registered via their neighborhood associations on the CRIUGM website. If they needed more information on the study, they had the option of calling someone at the CRIUGM. A total of 198 individuals registered on the web platform. They were contacted by a staff member of the research team for an interview by phone. During this phone call, the objective of the study and its procedures were explained and the selection criteria for participants were validated. Following these calls, 72 (36.4%) of potential participants were excluded because of the selection criteria and 126 (63.6%) individuals were enrolled, signed the consent form, and randomized into intervention (n = 63) and control (n = 63) groups. Among them, 11 (8.7%; 3 in the intervention and 8 in the control group) withdrew their consent before the baseline assessment. In total, 115 (91.3%) participants (60 in the intervention group and 55 in the control group) underwent the full baseline assessment. Seven (6.1%) participants in the intervention group and 2 (1.7%) in the control group dropped out over the 3-month period of the study. There was no significant difference in baseline characteristics between the group of participants who withdrew their consent and dropped out, and the group of those who completed the study (data not shown). Figure 1 shows a flow diagram detailing participant selection and follow-up in the RCT.

      Consort flow diagram detailing selection and follow-up of participants in the RCT.

      Intervention

      The intervention consisted of a 3-month cycle of weekly virtual MMFA guided tours. Each visit was performed with a group of 6 to 8 participants and a trained guide, for a total of 8 groups. Participants met once a week over the 3-month period and participated in a 45-minute virtual guided tour via the videoconferencing platform Zoom, using their own digital device. An additional 15-minute period dedicated to informal discussion (to allow for more socializing) was proposed after each tour (this extra discussion time was optional).

      Regardless of the topics or the themes covered, each visit was standardized and separated into three consecutive phases: presentation of the visit objectives, a dialogic-style tour with trained museum guides, and an open-ended discussion after the tour. The tour content consisted of a combination of images of artworks (e.g., paintings, sculpture, decorative pieces), live discussions animated by the tour guides, ancillary information on the artworks or artists from tour guides, and pre-recorded videos about specific works or artists. The amount and difficulty of information presented to participants was increased each month over the 3-month cycle of guided museum tours.

      Each weekly guided tour was unique and led by a single museum guide. One guide was assigned to each group of 8 participants for all 12 visits. Additionally, one member of the research team was assigned to each group to oversee the research components of the tour, participate in a virtual ethnography, manage participants' potential technical issues (e.g., difficulties connecting to the Zoom meeting, issues with sound, display) and assist in the presentation of the visual content (images and videos).

      Assessment Baseline assessment

      The baseline assessment was performed at participants' place of living via a web platform using standardized procedures and digital questionnaires before (M0) the first tour with support by phone if needed. Both the intervention and control groups performed the baseline assessment. The participants' socio-demographic characteristics (i.e., age, sex, ethnicity, place of living) were recorded. Social isolation was assessed using the 11-item Duke Social Support Index (DSSI) (21). The index comprises two subscales: social interaction (i.e., frequency of interactions) and subjective support (i.e., satisfaction with emotional support provided). DSSI scores range from 11 to 33, with higher scores indicating higher levels of social inclusion. Wellbeing was assessed using the Warwick-Edinburgh Mental Wellbeing Scale (WEMWBS) self-administered questionnaire (22), which is composed of 14 positively-worded items and produces scores ranging from 14 (i.e., none of the time) to 70 (i.e., all the time). EuroQol-5D (EQ-5D) was used to assess health-related quality of life (23). This tool is composed of a questionnaire examining physical health issues, with scores ranging from 0 (i.e., no issue) to 25 (i.e., worst issues), and a visual analog scale (VAS) assessing self-perceived health, ranging from 0 (i.e., worst health imaginable) to 100 (i.e., best health imaginable). Physical and mental frailty was assessed using the Center of Excellence Self-AdMinistered questionnaire (CESAM) (19, 24). Using 20 close-ended questions, CESAM examines different subdomains of mental and physical health: weight loss; polypharmacy (i.e., number of therapeutic classes taken on a daily basis ≥ 5); vision, hearing and memory problems; home support; activities of daily living (ADL) and instrumental activities of daily living (IADL) (25, 26); mood; practice of regular physical activity; and history of falls in the past 12 months. CESAM was filled out by the participants themselves under the supervision of Principal Investigator representatives. The total health frailty score ranges from 0 (i.e., best health condition) to 18 (i.e., worst health condition).

      Follow-up assessments

      DSSI, WEMWBS, EQ-5D and CESAM questionnaires were repeated after the twelfth (M3) tour in intervention and control groups. Like the baseline assessment, all questionnaires were completed online at participants' place of living with support by phone if needed. After the M3 assessment, the participants in the control group were offered a complimentary virtual MMFA tour to compensate them for their compliance and restraint from art and museum-going activities during the period of the study.

      Outcome measures

      The primary outcome was captured by the DSSI score. The secondary outcomes were captured by the scores of WEMWBS, EQ-5D and CESAM. For each outcome, the mean score at M0 and M3, and changes in mean score between M0 and M3 {using the formula [(score M3 – score M0) / (score M3 + score M0) /2] × 100} were used (19).

      Ethical considerations

      Participants were included after giving written, informed consent for research. The study was approved by the CIUSSS Center-Sud-de-l'Île-de-Montréal (Quebec, Canada) Research Ethics Committee (# 2022-1338 – CÉR VN 21-22-08).

      Statistics

      Means, standard deviations (SD), frequencies and percentages are used to describe participants' characteristics. Inter- and intra-group comparisons were performed using unpaired or paired t-tests, and Chi-squared tests, as appropriate. Multiple linear regressions were used to examine the association between variations of each questionnaire's score (used as dependent variables with separated models for each score) and the intervention (used as independent variables), were adjusted according to participants' baseline characteristics. P-values less than 0.05 were considered statistically significant for linear regressions. All statistics were performed using SPSS (version 23.0; SPSS, Inc., Chicago, IL).

      Results

      As shown in Table 1, there was no significant difference between groups for participants' baseline characteristics, except for sex and ethnicity. There were fewer females and Caucasians in the intervention group compared to the control group (P ≤ 0.013). There were significant greater mean scores for DSSI, EQ-5D and CESAM (P ≤ 0.001) at M3 compared to M0 in the intervention group (Table 2). There was only a trend (P = 0.059) for greater WEMWBS mean scores in the intervention group. No significant change in all scales' scores between M0 and M3 was found in the control group. Inter-group comparisons showed that DSSI, WEMWBS, EQ-5D and CESAM mean scores were significantly higher in the intervention group compared to the control group at M3 (P < 0.033), while significant difference was found at M0. Table 3 shows that participation in weekly virtual MMFA tours was significantly associated with improvements in all scales (P ≤ 0.012).

      Baseline participant characteristics (n = 106).

      Participants P-Value*
      Control (n = 53) Intervention (n = 53)
      Age (years), mean ± SD 74.3 ± 5.1 75.0 ± 4.6 0.458
      Female, n (%) 48 (90.6) 38 (71.7) 0.013
      Caucasian, n (%) 53 (100) 45 (84.9) 0.003
      Place of living home, n (%) 47 (88.7) 46 (86.8) 0.696
      Living alone, n (%) 33 (62.3) 36 (67.9) 0.838
      Home support, n (%) 1 (1.9) 3 (5.7) 0.308
      ADL score (/6), mean ± SD 5.8 ± 0.5 5.6 ± 0.8 0.233
      IADL score (/4)ǁ, mean ± SD 3.9 ± 0.2 3.9 ± 0.2 1.000
      Polypharmacy§, n (%) 38 (71.7) 43 (81.1) 0.253
      SARS-CoV2 status, n (%)
      Never infected 4 (7.5) 4 (7.5) 1.000
      Vaccinated 51 (96.2) 53 (100.0) 0.153
      Happy mood, n (%) 23 (43.4) 27 (50.9) 0.436
      Practice of physical activity**, n (%) 46 (86.8) 37 (69.8) 0.034
      History of falls in the past 12 months, n (%) 16 (30.2) 14 (26.4) 0.666

      SD, Standard deviation; ADL, Activities of daily living; IADL, Instrumental activities of daily living;

      Comparison based on unpaired t-tests or chi-squared, as appropriate;

      Receiving help from family, friend or professional for daily living activities;

      Ranging from 0 (dependent) to 6 (independent);

      Ranging from 0 (non-autonomous) to 4 (autonomous);

      Number of therapeutic classes taken daily ≥ 5;

      Answer to the question “How do you feel today?” with three possible answers, including unhappy, happy, neither one nor the other;

      Regular physical activity (walking, bicycle, etc.) at least 1 h per week in the past month; P-value significant fixed < 0.0035 because of multiple comparisons (n = 14).

      Comparisons of mean values of scales assessing social isolation, wellbeing, quality of life and frailty between control and intervention groups (n = 106).

      Participants P-value between group comparisons
      Control (n = 53) Intervention (n = 53) M0 M3
      M0 M3 P-Value* M0 M3 P-Value*
      11-item Duke Social Support Index (/33), mean ± SD 25.3 ± 2.7 25.7 ± 3.2 0.240 24.6 ± 3.1 27.1 ± 3.2 ≤0.001 0.205 0.033
      Warwick-Edinburgh Wellbeing scale (/70), mean ± SD 54.6 ± 6.3 53.6 ± 4.7 0.359 56.6 ± 6.4 58.3 ± 5.5 0.059 0.109 ≤0.001
      EQ-5D, mean ± SD
      Questionnaire score (/25)ǁ 6.6 ± 1.6 7.0 ± 2.0 0.052 6.8 ± 2.0 8.6 ± 2.1 ≤0.001 0.747 ≤0.001
      Visual analog scale (/100)§ 78.5 ± 11.5 78.5 ± 14.2 0.992 77.5 ± 14.2 86.6 ± 10.5 ≤0.001 0.686 0.001
      Frailty Score (/18)#, mean±SD 6.2 ± 3.3 5.4 ± 2.4 0.177 6.7 ± 4.0 2.1 ± 1.0 ≤0.001 0.464 ≤0.001

      SD, Standard deviation; EQ-5D, EuroQuol 5D; M, Month; M0, baseline assessment before intervention; M3, Assessment at the end of the 3-month intervention period;

      Comparisons based on paired t-test;

      Ranging from 11 (social isolation) to 33 (absence of social isolation);

      Ranging from 14 (i.e., none of the time) to 70 (i.e., all the time);

      Ranging from 0 (no problem) to 25 (unable to do);

      Ranging from 0 (the worst health condition) to 100 (the best health condition);

      Mean score calculated from computerized self-administered questionnaire composed of 20 questions providing a score ranging from 0 (vigorous) to 18 (severe frailty);

      Comparison based on unpaired t-tests; significant P-values in bold fixed at < 0.003 because of multiples comparisons (n = 15).

      Multiple linear regressions showing the association of intervention (i.e., 3-month period of virtual guided tour, independent variable) and changes in mean score between baseline assessment and end of intervention for 11-item Duke Social Support Index, Warwick-Edinburgh Wellbeing scale, EuroQol-5D and Center of Excellence Self-AdMinistered questionnaire scores adjusted for baseline participant's characteristics (n = 106).

      Change in mean score between baseline assessment and the end of intervention* Effect of intervention
      β [95%CI] P-Value
      11-item DSSI 10.58 [5.44–15.72] ≤0.001
      WEMWBS score 7.49 [1.71–13.27] 0.012
      EQ-5D
      Score 19.23 [10.55–27.91] ≤0.001
      VAS 14.93 [7.34–22.53] ≤0.001
      CESAM score 33.86 [18.22–49.50] ≤0.001

      calculated form the formula ((M3-M0) / ((M3+M0)/2)) x 100 and expressed in percentage; β, Coefficient of regression beta; CI, confident interval; DSSI, Duke Social Support Index; WEMWBS, Warwick-Edinburgh Well-being scale; EQ-5D, EuroQol-5D; VAS, Visual analogic scale; CESAM, Center of Excellence Self-AdMinistered questionnaire; The bold values indicate the significant values of p < 0.05.

      Discussion

      The findings of this RCT show that the 3-month cycle of weekly virtual MMFA tours had multidimensional benefits in participating older adults. Social isolation decreased and both physical and mental health improved significantly.

      The decrease in social isolation reported in our study is consistent with the results of previous studies, which have shown that arts-based activities can reduce social isolation, and that these interventions are most effective when they are practiced in a group setting and actively engage participants (1013). In addition, a meta-analysis previously demonstrated that interventions that focus on changing a person's perceptions and that stimulate positive emotions are more beneficial than those that focus on building social ties (15). Furthermore, interventions involving cultural activities, such as the visual arts, regardless of artistic genre or type of activity, have demonstrable benefits including the generation of positive emotions, which have been shown to improve wellbeing, self-esteem and quality of life (16, 17). We suggest that it is for all these reasons that we observed significant social and health benefits in our RCT.

      Social isolation is a major problem in Canadian society. The proportion of Canadians aged 65 and over who report experiencing social isolation is high: in 2018, it was estimated to be around 20% of the older population, representing 1.5 million people (27, 28). Social isolation in combination with health challenges, which are often prevalent as we age, expose older individuals and the wider community to a variety of adverse outcomes with deleterious effects (5, 6). For instance, lack of contact between members of a family or within society may hamper or break down intergenerational relationships, increasing feelings of social isolation (29, 30). The physical and mental health issues known to arise as a result of social isolation may increase people's needs for health and social services, which puts pressure on those who work in these systems. This may in turn increase service expenditures (5, 6). Indeed, in 2016, the International Federation on Aging reported that “the main new problem facing seniors in Canada is maintaining their social contacts and activities” (31). This highlights the need for effective interventions that promote the social inclusion of older adults before they experience social isolation. The 3-month cycle of weekly virtual MMFA tours examined in our study seems to be one example of an intervention that effectively created social connection, the opposite of social isolation.

      Many museums offer participatory arts-based activities (19, 3237). The United Kingdom was one of the first countries to consider museums as partners in social and health policy. This gave rise to a consortium known as National Alliance for Museums, Health and Wellbeing, “(2015-2018), which became a driving force in the British Ministry of Health and Social Services 1 and is now known as the Culture, Health and Wellbeing Alliance. The interventions offered in British museums are most often interactive and participatory group activities 1. In the same period in Canada, the MMFA began developing participatory, arts-based activities in 2015 (19). Like their British counterparts, the MMFA focused on participatory, art-making workshops, for which improvements in the quality of life and wellbeing of community-dwelling older adults, as well as a reduction in their physical frailty, were reported (19, 31, 32). Our RCT reproduces and confirms previous studies that demonstrate the benefits of thoughtful, interactive, participatory arts-based programming on the physical and mental health of older adults interested in art and culture. The observation that arts-based activities can be beneficial to physical and mental health is not a new one, as exemplified by the field of art therapy (3235). Improvements in wellbeing and quality of life have been reported in patients with cancer, neuropsychiatric diseases, or physical disabilities (32, 35). Unlike previous studies, this investigation of the MMFA and the guided tours that they developed during the COVID-19 pandemic is the first time, to the best of our knowledge, that these benefits have been documented and reported on virtual museum tours. Taken together, these findings suggest that arts-based activities, even when delivered online, retain their health benefits for older adults. A causal explanation of these complex health benefits is likely attributable to the dynamic interaction between wellbeing, health-related quality of life and physical health. Indeed, a sequence of health benefits has been suggested in previous studies (19). To summarize, the positive experiences engendered by arts-based activities delivered online may improve wellbeing, which improves quality of life and finally, physical and mental health when they incorporate into this virtual environment the principles mentioned previously: an emphasis on group activities; goal-oriented, purposive endeavors; and activities with a creative component.

      The RCT design and the standardization of the 3-month cycle of weekly virtual MMFA tours were the main strengths of our study. However, some limitations need to be considered. First, the RCT was carried out in the older population living exclusively in Montreal. Second, even if benefits were reported for social isolation, physical and mental health, it is not possible to identify and isolate respective causal mechanisms. For example, mental and physical health benefits may result from the break in social isolation experienced because of participants', engagement in the study itself. Third, how much “control” we had over the control group was impossible to monitor with precision. Over the study period, the control group may have been exposed to activities that may have influenced the RCT outcomes. We tried to limit this effect by asking the control group participants to withhold participation any in arts-related interventions and social programs over the study period. No participants in the control group reported arts-related or social program activities, however, it was beyond our mandate to monitor. Fourth, there were significant differences between the intervention and control groups' baseline characteristics. In both groups there was a high proportion of females. However, this proportion differed significantly, with fewer females in the intervention group. Sex is a biological characteristic that may differentially impact the outcomes assessed in our RCT. Furthermore, there were also fewer Caucasians in the intervention group and this difference in ethnicity also could affect the results. However, it should be noted that all linear regression models were adjusted based on these baseline characteristics in order to limit their impact.

      Conclusion

      Our RCT suggests that a 3-month cycle of weekly virtual MMFA tours may decrease social isolation, foster a sense of connectedness and, thereby, improve mental and physical health in community-dwelling older adults. Like other arts-based activities, this particular program, delivered online, appears to have been an effective digital cultural intervention to mitigate social isolation and the progression of physical frailty, positioning museums as key stakeholders for social and health prevention, and for fostering social connectedness, in the aging population.

      Data availability statement

      The datasets used and analyzed in the current study will be made available by the corresponding author upon reasonable request. Requests should be sent to the corresponding author: OB, PhD; Research Centre of the Geriatric University Institute of Montreal, Montreal, QC, Canada; olivier.beauchet@umontreal.ca. All requests need a cover letter explaining the objective, justification, and referent Ethics Committee.

      Ethics statement

      The study received approval from the CIUSSS Centre-Sud-de-l'Île-de-Montréal (Quebec, Canada) Research Ethics Committee approved the study (# 2022-1338 – CÉR VN 21-22-08). The patients/participants provided their written informed consent to participate in this study.

      Author contributions

      OB: principal investigator, study conception and design, obtaining funding, drafting the manuscript, revision of the manuscript, and final approval of the manuscript. JM, KG, CL, and KS: drafting the manuscript, revision of the manuscript, and final approval of the manuscript. All authors contributed to the article and approved the submitted version.

      Funding

      This trial was funded by Fonds de Recherche du Québec Société et culture; Actions concertées / Action sur le vieillissement actif de la population au Québec / Projet de recherche-action – Project 281107. The funding source had no role in the design of the nor on execution, data management, analyses, interpretation, or publication of the results.

      Conflict of interest

      The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

      Publisher's note

      All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

      We thank the museum guides and all members of the Direction of Education and Wellness of the MMFA. We thank also Amy Lee, the Chinese mandarin translator, all the members of the Service à la Famille Chinoise du Grand Montréal, Annie-Hélène Samson and the involved students of Dawson College.

      References Epton T Ghio D Ballard LM Allen SF Kassianos AP Hewitt R . Interventions to promote physical distancing behaviour during infectious disease pandemics or epidemics: a systematic review. Soc Sci Med. (2022) 303:114946. 10.1016/j.socscimed.2022.11494635605431 Ernst M Niederer D Werner AM Czaja SJ Mikton C Ong AD . Loneliness before and during the COVID-19 pandemic: a systematic review with meta-analysis. Am Psychol. (2022) (in press). 10.31234/osf.io/wjx5v35533109 Beauchet O Cooper-Brown L Ivensky V Launay CP. Telemedicine for housebound older persons during the Covid-19 pandemic. Maturitas. (2020) 142:810. 10.1016/j.maturitas.2020.06.02433158491 Launay CP Cooper-Brown L Ivensky V Beauchet O. Frailty phenotype of homebound montreal older community dwellers during the COVID-19 pandemic: results of a cross-sectional population study. J Frailty Aging. (2021) 10:1912. 10.14283/jfa.2020.6933575713 Morley JE Vellas B Van Kan GA Anker SD Bauer JM Bernabei R . Frailty consensus: a call to action. J Am Med Dir Assoc. (2013) 14:3927. 10.1016/j.jamda.2013.03.02223764209 Mitnitski AB Rutenberg AD Farrell S Rockwood K. Aging, frailty and complex networks. Biogerontology. (2017) 18:43346. 10.1007/s10522-017-9684-x28255823 Fédération internationale du vieillissement. Current emerging issues facing older Canadians. 2014. (2012) Available online at: https://www.ifa-fiv.org/wp-content/uploads/2012/12/current-and-emerging-issues-facing-older-canadians-final-report-30-march-2012.pdf (accessed October 2019). Courtin E Knapp M. Social isolation, loneliness and health in old age: a scoping review. Health Soc Care Commun. (2017) 25:799812. 10.1111/hsc.1231126712585 Cotterell N Buffel T Phillipson C. Preventing social isolation in older people. Maturitas. (2018) 113:804 10.1016/j.maturitas.2018.04.01429903652 Chipps J Jarvis MA Ramlall S. The effectiveness of e-interventions on reducing social isolation in older persons: a systematic review of systematic reviews. J Telemed Telecare. (2017) 23:81727. 10.1177/1357633X1773377328958209 Landeiro F Barrows P Nuttall Musson E Gray AM Leal J. Reducing social isolation and loneliness in older people: a systematic review protocol. BMJ Open. (2017) 7:e013778. 10.1136/bmjopen-2016-01377828515187 Gardiner C Geldenhuys G Gott M. Interventions to reduce social isolation and loneliness among older people: an integrative review. Health Soc Care Commun. (2018) 26:14757. 10.1111/hsc.1236727413007 Cattan M White M Bond J Learmouth A. Preventing social isolation and loneliness among older people: a systematic review of health promotion interventions. Ageing Soc. (2005) 25:41. 10.1017/S0144686X0400259427736564 Dickens AP Richards SH Greaves CJ Campbell JL. Interventions targeting social isolation in older people: a systematic review. BMC Public Health. (2011) 11:647. 10.1186/1471-2458-11-64729199121 Masi CM Chen HY Hawkley LC Cacioppo JT, A. meta-analysis of interventions to reduce loneliness. Pers Soc Psychol Rev. (2011) 15:21966. 10.1177/108886831037739420716644 Jensen A Bonde LO. The use of arts interventions for mental health and wellbeing in health settings. Perspect Public Health. (2018) 138:20914. 10.1177/175791391877260229708025 Jensen A. Beyond the borders: the use of art participation for the promotion of health and well-being in Britain and Denmark. Arts Health. (2013) 5:20415. 10.1080/17533015.2013.81744825729410 Shannon K Bail K Neville S. Dementia-friendly community initiatives: an integrative review. J Clin Nurs. (2019) 28:203545. 10.1111/jocn.1474630554458 Beauchet O Bastien T Mittelman M Hayashi Y Ho A. Participatory art-based activity, community-dwelling older adults and changes in health condition: Results from a pre-post intervention, single arm, prospective and longitudinal study. Maturitas. (2020) 134:814. 10.1016/j.maturitas.2020.01.00632143777 Moher D Hopewell S Schulz KF Montori V Gøtzsche PC Devereaux PJ . CONSORT 2010 explanation and elaboration: updated guidelines for reporting parallel group randomised trials. Int J Surg. (2012) 10:2855. 10.1016/j.ijsu.2011.10.00122036893 Koenig HG Westlund RE George LK Hughes DC Blazer DG Hybels C. Abbreviating the duke social support index for use in chronically ill elderly individuals. Psychosomatics. (1993) 34:619. 10.1016/S0033-3182(93)71928-38426892 Tennant R Hiller L Fishwick R Platt S Joseph S Weich S . The warwick-edinburgh mental well-being scale (WEMWBS): development and UK validation. Health Qual Life Outcomes. (2007) 5:63. 10.1186/1477-7525-5-6318042300 Brooks P. EuroQol: the current state of play. Health Policy. (1996) 37:5372. 10.1016/0168-8510(96)00822-610158943 Beauchet O Launay CP Merjagnan C Kabeshova A Annweiler C. Quantified self and comprehensive geriatric assessment: older adults are able to evaluate their own health and functional status. PLoS ONE. (2014) 9:e100636. 10.1371/journal.pone.010063624968016 Best Practices in Nursing Care to Older Adults. The Hartford Institute for Geriatric Nursing. New York University, College of Nursing. Available online at: www.hartfordign.org (accessed October 2019). Pérès K Chrysostome V Fabrigoule C Orgogozo JM Dartigues JF Barberger-Gateau P. Restriction in complex activities of daily living in MCI: impact on outcome. Neurology. (2006) 67:4616. 10.1212/01.wnl.0000228228.70065.f117470764 Gouvernement du Canada. Rapport sur l'isolement social des aînés, 2013-2014. Disponible en ligne. Available online at: https://www.canada.ca/fr/conseil-national-aines/programmes/publications-rapports/2014/isolement-social-aines/page05.html (accessed October 2019). Statistic Canada. Une population vieillissante. 2018. Disponible en ligne. Available online at: https://www150.statcan.gc.ca/n1/pub/11-402-x/2010000/pdf/population-fra.pdf (accessed October 2019). O'Rourke HM Collins L Sidani S. Interventions to address social connectedness and loneliness for older adults: a scoping review. BMC Geriatr. (2018) 18:214. 10.1186/s12877-018-0897-x30219034 Medical Advisory Secretariat. Social isolation in community-dwelling seniors: an evidence-based analysis. Ont Health Technol Assess Ser. (2008) 8:149. Fédération internationale du vieillissement. Current Emerging Issues Facing Older Canadians. (2012). Available online at: https://www.ifa-fiv.org/wp-content/uploads/2012/12/current-and-emerging-issues-facing-older-canadians-final-report-30-march-2012.pdf (accessed October 2019). Perruzza N Kinsella EA. Creative arts occupations in therapeutic practice: a review of the literature. Br J Occup Therapy. (2010) 73:2618. 10.4276/030802210X12759925468943 Deshmukh SR Holmes J Cardno A. Art therapy for people with dementia. Cochrane Database Syst Rev. (2018) 9:CD011073. 10.1002/14651858.CD011073.pub230215847 Todd C Camic PM Lockyer B Thomson LJM Chatterjee HJ. Museum-based programs for socially isolated older adults: understanding what works. Health Place. (2017) 48:4755. 10.1016/j.healthplace.2017.08.00528934636 Camic PM Chatterjee HJ. Museums and art galleries as partners for public health interventions. Perspect Public Health. (2013) 133:6671. 10.1177/175791391246852323308010 Beauchet O Cooper-Brown LA Hayashi Y Deveault M Launay CP. Improving the mental and physical health of older community-dwellers with a museum participatory art-based activity: results of a multicentre randomized controlled trial. Aging Clin Exp Res. (2022) (in press). 10.1007/s40520-022-02139-335578103 Beauchet O Cooper-Brown LA Hayashi Y Deveault M Ho AHY Launay CP. Health benefits of “Thursdays at the Montreal Museum of Fine Arts”: results of a randomized clinical trial. Maturitas. (2021) 153:2632. 10.1016/j.maturitas.2021.07.01334654525 Abbreviations ADL

      Activities of daily living

      CRIUGM

      Research Center of the Geriatric University Institute of Montreal

      CESAM

      Center of Excellence Self-AdMinistred questionnaire

      DSSI

      Duke Social Support Index

      EQ-5D

      EuroQol-5D

      IADL

      Instrumental activities of daily living

      MMFA

      Montreal Museum of Fine Arts

      VAS

      visual analogic scale

      WEMWBS

      Warwick-Edinburgh Mental Wellbeing Scale.

      1https://www.google.ca/search?sxsrf=ACYBGNTU3BtvG3NM3zq7ZcuxogmZxn45qA%3A1580848264124&source=hp&ei=iNQ5XreMBfCh_Qb4pb-YAg&q=2018+English+Alliance+of+Museums+for+Health+and+Wellbeing&oq=2018+English+Alliance+of+Museums+for+Health+and+Wellbeing&gs_l=psy-ab.3.0.0.1306.9211.0.12174.0.0.6.0.0.0.124.745.10j1.0.0.0.0.0.0.0.0.0.1j2..gws-wiz.0.0.0.0.0.0.0i131j0j35i39j0i22i30j0i22i10i30.z4JigKYWf4U&ved=0ahUKEwi38OXZ3rjnAhXwUN8KHfjSDyMQ4dUDCAs&uact=5#spf=1580848276734

      2https://www.blueprintincome.com/tools/life-expectancy-calculator-how-long-will-i-live/

      ‘Oh, my dear Thomas, you haven’t heard the terrible news then?’ she said. ‘I thought you would be sure to have seen it placarded somewhere. Alice went straight to her room, and I haven’t seen her since, though I repeatedly knocked at the door, which she has locked on the inside, and I’m sure it’s most unnatural of her not to let her own mother comfort her. It all happened in a moment: I have always said those great motor-cars shouldn’t be allowed to career about the streets, especially when they are all paved with cobbles as they are at Easton Haven, which are{331} so slippery when it’s wet. He slipped, and it went over him in a moment.’ My thanks were few and awkward, for there still hung to the missive a basting thread, and it was as warm as a nestling bird. I bent low--everybody was emotional in those days--kissed the fragrant thing, thrust it into my bosom, and blushed worse than Camille. "What, the Corner House victim? Is that really a fact?" "My dear child, I don't look upon it in that light at all. The child gave our picturesque friend a certain distinction--'My husband is dead, and this is my only child,' and all that sort of thing. It pays in society." leave them on the steps of a foundling asylum in order to insure [See larger version] Interoffice guff says you're planning definite moves on your own, J. O., and against some opposition. Is the Colonel so poor or so grasping—or what? Albert could not speak, for he felt as if his brains and teeth were rattling about inside his head. The rest of[Pg 188] the family hunched together by the door, the boys gaping idiotically, the girls in tears. "Now you're married." The host was called in, and unlocked a drawer in which they were deposited. The galleyman, with visible reluctance, arrayed himself in the garments, and he was observed to shudder more than once during the investiture of the dead man's apparel. HoME香京julia种子在线播放 ENTER NUMBET 0016juhohw.com.cn
      hetcoinex.com.cn
      hbcxwm.com.cn
      epepiy.com.cn
      sdyart.org.cn
      www.qg717.net.cn
      wdclqz.org.cn
      www.seniorlion.com.cn
      opwpym.com.cn
      wztnre.com.cn
      处女被大鸡巴操 强奸乱伦小说图片 俄罗斯美女爱爱图 调教强奸学生 亚洲女的穴 夜来香图片大全 美女性强奸电影 手机版色中阁 男性人体艺术素描图 16p成人 欧美性爱360 电影区 亚洲电影 欧美电影 经典三级 偷拍自拍 动漫电影 乱伦电影 变态另类 全部电 类似狠狠鲁的网站 黑吊操白逼图片 韩国黄片种子下载 操逼逼逼逼逼 人妻 小说 p 偷拍10幼女自慰 极品淫水很多 黄色做i爱 日本女人人体电影快播看 大福国小 我爱肏屄美女 mmcrwcom 欧美多人性交图片 肥臀乱伦老头舔阴帝 d09a4343000019c5 西欧人体艺术b xxoo激情短片 未成年人的 插泰国人夭图片 第770弾み1 24p 日本美女性 交动态 eee色播 yantasythunder 操无毛少女屄 亚洲图片你懂的女人 鸡巴插姨娘 特级黄 色大片播 左耳影音先锋 冢本友希全集 日本人体艺术绿色 我爱被舔逼 内射 幼 美阴图 喷水妹子高潮迭起 和后妈 操逼 美女吞鸡巴 鸭个自慰 中国女裸名单 操逼肥臀出水换妻 色站裸体义术 中国行上的漏毛美女叫什么 亚洲妹性交图 欧美美女人裸体人艺照 成人色妹妹直播 WWW_JXCT_COM r日本女人性淫乱 大胆人艺体艺图片 女同接吻av 碰碰哥免费自拍打炮 艳舞写真duppid1 88电影街拍视频 日本自拍做爱qvod 实拍美女性爱组图 少女高清av 浙江真实乱伦迅雷 台湾luanlunxiaoshuo 洛克王国宠物排行榜 皇瑟电影yy频道大全 红孩儿连连看 阴毛摄影 大胆美女写真人体艺术摄影 和风骚三个媳妇在家做爱 性爱办公室高清 18p2p木耳 大波撸影音 大鸡巴插嫩穴小说 一剧不超两个黑人 阿姨诱惑我快播 幼香阁千叶县小学生 少女妇女被狗强奸 曰人体妹妹 十二岁性感幼女 超级乱伦qvod 97爱蜜桃ccc336 日本淫妇阴液 av海量资源999 凤凰影视成仁 辰溪四中艳照门照片 先锋模特裸体展示影片 成人片免费看 自拍百度云 肥白老妇女 女爱人体图片 妈妈一女穴 星野美夏 日本少女dachidu 妹子私处人体图片 yinmindahuitang 舔无毛逼影片快播 田莹疑的裸体照片 三级电影影音先锋02222 妻子被外国老头操 观月雏乃泥鳅 韩国成人偷拍自拍图片 强奸5一9岁幼女小说 汤姆影院av图片 妹妹人艺体图 美女大驱 和女友做爱图片自拍p 绫川まどか在线先锋 那么嫩的逼很少见了 小女孩做爱 处女好逼连连看图图 性感美女在家做爱 近距离抽插骚逼逼 黑屌肏金毛屄 日韩av美少女 看喝尿尿小姐日逼色色色网图片 欧美肛交新视频 美女吃逼逼 av30线上免费 伊人在线三级经典 新视觉影院t6090影院 最新淫色电影网址 天龙影院远古手机版 搞老太影院 插进美女的大屁股里 私人影院加盟费用 www258dd 求一部电影里面有一个二猛哥 深肛交 日本萌妹子人体艺术写真图片 插入屄眼 美女的木奶 中文字幕黄色网址影视先锋 九号女神裸 和骚人妻偷情 和潘晓婷做爱 国模大尺度蜜桃 欧美大逼50p 西西人体成人 李宗瑞继母做爱原图物处理 nianhuawang 男鸡巴的视屏 � 97免费色伦电影 好色网成人 大姨子先锋 淫荡巨乳美女教师妈妈 性nuexiaoshuo WWW36YYYCOM 长春继续给力进屋就操小女儿套干破内射对白淫荡 农夫激情社区 日韩无码bt 欧美美女手掰嫩穴图片 日本援交偷拍自拍 入侵者日本在线播放 亚洲白虎偷拍自拍 常州高见泽日屄 寂寞少妇自卫视频 人体露逼图片 多毛外国老太 变态乱轮手机在线 淫荡妈妈和儿子操逼 伦理片大奶少女 看片神器最新登入地址sqvheqi345com账号群 麻美学姐无头 圣诞老人射小妞和强奸小妞动话片 亚洲AV女老师 先锋影音欧美成人资源 33344iucoom zV天堂电影网 宾馆美女打炮视频 色五月丁香五月magnet 嫂子淫乱小说 张歆艺的老公 吃奶男人视频在线播放 欧美色图男女乱伦 avtt2014ccvom 性插色欲香影院 青青草撸死你青青草 99热久久第一时间 激情套图卡通动漫 幼女裸聊做爱口交 日本女人被强奸乱伦 草榴社区快播 2kkk正在播放兽骑 啊不要人家小穴都湿了 www猎奇影视 A片www245vvcomwwwchnrwhmhzcn 搜索宜春院av wwwsee78co 逼奶鸡巴插 好吊日AV在线视频19gancom 熟女伦乱图片小说 日本免费av无码片在线开苞 鲁大妈撸到爆 裸聊官网 德国熟女xxx 新不夜城论坛首页手机 女虐男网址 男女做爱视频华为网盘 激情午夜天亚洲色图 内裤哥mangent 吉沢明歩制服丝袜WWWHHH710COM 屌逼在线试看 人体艺体阿娇艳照 推荐一个可以免费看片的网站如果被QQ拦截请复制链接在其它浏览器打开xxxyyy5comintr2a2cb551573a2b2e 欧美360精品粉红鲍鱼 教师调教第一页 聚美屋精品图 中韩淫乱群交 俄罗斯撸撸片 把鸡巴插进小姨子的阴道 干干AV成人网 aolasoohpnbcn www84ytom 高清大量潮喷www27dyycom 宝贝开心成人 freefronvideos人母 嫩穴成人网gggg29com 逼着舅妈给我口交肛交彩漫画 欧美色色aV88wwwgangguanscom 老太太操逼自拍视频 777亚洲手机在线播放 有没有夫妻3p小说 色列漫画淫女 午间色站导航 欧美成人处女色大图 童颜巨乳亚洲综合 桃色性欲草 色眯眯射逼 无码中文字幕塞外青楼这是一个 狂日美女老师人妻 爱碰网官网 亚洲图片雅蠛蝶 快播35怎么搜片 2000XXXX电影 新谷露性家庭影院 深深候dvd播放 幼齿用英语怎么说 不雅伦理无需播放器 国外淫荡图片 国外网站幼幼嫩网址 成年人就去色色视频快播 我鲁日日鲁老老老我爱 caoshaonvbi 人体艺术avav 性感性色导航 韩国黄色哥来嫖网站 成人网站美逼 淫荡熟妇自拍 欧美色惰图片 北京空姐透明照 狼堡免费av视频 www776eom 亚洲无码av欧美天堂网男人天堂 欧美激情爆操 a片kk266co 色尼姑成人极速在线视频 国语家庭系列 蒋雯雯 越南伦理 色CC伦理影院手机版 99jbbcom 大鸡巴舅妈 国产偷拍自拍淫荡对话视频 少妇春梦射精 开心激动网 自拍偷牌成人 色桃隐 撸狗网性交视频 淫荡的三位老师 伦理电影wwwqiuxia6commqiuxia6com 怡春院分站 丝袜超短裙露脸迅雷下载 色制服电影院 97超碰好吊色男人 yy6080理论在线宅男日韩福利大全 大嫂丝袜 500人群交手机在线 5sav 偷拍熟女吧 口述我和妹妹的欲望 50p电脑版 wwwavtttcon 3p3com 伦理无码片在线看 欧美成人电影图片岛国性爱伦理电影 先锋影音AV成人欧美 我爱好色 淫电影网 WWW19MMCOM 玛丽罗斯3d同人动画h在线看 动漫女孩裸体 超级丝袜美腿乱伦 1919gogo欣赏 大色逼淫色 www就是撸 激情文学网好骚 A级黄片免费 xedd5com 国内的b是黑的 快播美国成年人片黄 av高跟丝袜视频 上原保奈美巨乳女教师在线观看 校园春色都市激情fefegancom 偷窥自拍XXOO 搜索看马操美女 人本女优视频 日日吧淫淫 人妻巨乳影院 美国女子性爱学校 大肥屁股重口味 啪啪啪啊啊啊不要 操碰 japanfreevideoshome国产 亚州淫荡老熟女人体 伦奸毛片免费在线看 天天影视se 樱桃做爱视频 亚卅av在线视频 x奸小说下载 亚洲色图图片在线 217av天堂网 东方在线撸撸-百度 幼幼丝袜集 灰姑娘的姐姐 青青草在线视频观看对华 86papa路con 亚洲1AV 综合图片2区亚洲 美国美女大逼电影 010插插av成人网站 www色comwww821kxwcom 播乐子成人网免费视频在线观看 大炮撸在线影院 ,www4KkKcom 野花鲁最近30部 wwwCC213wapwww2233ww2download 三客优最新地址 母亲让儿子爽的无码视频 全国黄色片子 欧美色图美国十次 超碰在线直播 性感妖娆操 亚洲肉感熟女色图 a片A毛片管看视频 8vaa褋芯屑 333kk 川岛和津实视频 在线母子乱伦对白 妹妹肥逼五月 亚洲美女自拍 老婆在我面前小说 韩国空姐堪比情趣内衣 干小姐综合 淫妻色五月 添骚穴 WM62COM 23456影视播放器 成人午夜剧场 尼姑福利网 AV区亚洲AV欧美AV512qucomwwwc5508com 经典欧美骚妇 震动棒露出 日韩丝袜美臀巨乳在线 av无限吧看 就去干少妇 色艺无间正面是哪集 校园春色我和老师做爱 漫画夜色 天海丽白色吊带 黄色淫荡性虐小说 午夜高清播放器 文20岁女性荫道口图片 热国产热无码热有码 2015小明发布看看算你色 百度云播影视 美女肏屄屄乱轮小说 家族舔阴AV影片 邪恶在线av有码 父女之交 关于处女破处的三级片 极品护士91在线 欧美虐待女人视频的网站 享受老太太的丝袜 aaazhibuo 8dfvodcom成人 真实自拍足交 群交男女猛插逼 妓女爱爱动态 lin35com是什么网站 abp159 亚洲色图偷拍自拍乱伦熟女抠逼自慰 朝国三级篇 淫三国幻想 免费的av小电影网站 日本阿v视频免费按摩师 av750c0m 黄色片操一下 巨乳少女车震在线观看 操逼 免费 囗述情感一乱伦岳母和女婿 WWW_FAMITSU_COM 偷拍中国少妇在公车被操视频 花也真衣论理电影 大鸡鸡插p洞 新片欧美十八岁美少 进击的巨人神thunderftp 西方美女15p 深圳哪里易找到老女人玩视频 在线成人有声小说 365rrr 女尿图片 我和淫荡的小姨做爱 � 做爱技术体照 淫妇性爱 大学生私拍b 第四射狠狠射小说 色中色成人av社区 和小姨子乱伦肛交 wwwppp62com 俄罗斯巨乳人体艺术 骚逼阿娇 汤芳人体图片大胆 大胆人体艺术bb私处 性感大胸骚货 哪个网站幼女的片多 日本美女本子把 色 五月天 婷婷 快播 美女 美穴艺术 色百合电影导航 大鸡巴用力 孙悟空操美少女战士 狠狠撸美女手掰穴图片 古代女子与兽类交 沙耶香套图 激情成人网区 暴风影音av播放 动漫女孩怎么插第3个 mmmpp44 黑木麻衣无码ed2k 淫荡学姐少妇 乱伦操少女屄 高中性爱故事 骚妹妹爱爱图网 韩国模特剪长发 大鸡巴把我逼日了 中国张柏芝做爱片中国张柏芝做爱片中国张柏芝做爱片中国张柏芝做爱片中国张柏芝做爱片 大胆女人下体艺术图片 789sss 影音先锋在线国内情侣野外性事自拍普通话对白 群撸图库 闪现君打阿乐 ady 小说 插入表妹嫩穴小说 推荐成人资源 网络播放器 成人台 149大胆人体艺术 大屌图片 骚美女成人av 春暖花开春色性吧 女亭婷五月 我上了同桌的姐姐 恋夜秀场主播自慰视频 yzppp 屄茎 操屄女图 美女鲍鱼大特写 淫乱的日本人妻山口玲子 偷拍射精图 性感美女人体艺木图片 种马小说完本 免费电影院 骑士福利导航导航网站 骚老婆足交 国产性爱一级电影 欧美免费成人花花性都 欧美大肥妞性爱视频 家庭乱伦网站快播 偷拍自拍国产毛片 金发美女也用大吊来开包 缔D杏那 yentiyishu人体艺术ytys WWWUUKKMCOM 女人露奶 � 苍井空露逼 老荡妇高跟丝袜足交 偷偷和女友的朋友做爱迅雷 做爱七十二尺 朱丹人体合成 麻腾由纪妃 帅哥撸播种子图 鸡巴插逼动态图片 羙国十次啦中文 WWW137AVCOM 神斗片欧美版华语 有气质女人人休艺术 由美老师放屁电影 欧美女人肉肏图片 白虎种子快播 国产自拍90后女孩 美女在床上疯狂嫩b 饭岛爱最后之作 幼幼强奸摸奶 色97成人动漫 两性性爱打鸡巴插逼 新视觉影院4080青苹果影院 嗯好爽插死我了 阴口艺术照 李宗瑞电影qvod38 爆操舅母 亚洲色图七七影院 被大鸡巴操菊花 怡红院肿么了 成人极品影院删除 欧美性爱大图色图强奸乱 欧美女子与狗随便性交 苍井空的bt种子无码 熟女乱伦长篇小说 大色虫 兽交幼女影音先锋播放 44aad be0ca93900121f9b 先锋天耗ばさ无码 欧毛毛女三级黄色片图 干女人黑木耳照 日本美女少妇嫩逼人体艺术 sesechangchang 色屄屄网 久久撸app下载 色图色噜 美女鸡巴大奶 好吊日在线视频在线观看 透明丝袜脚偷拍自拍 中山怡红院菜单 wcwwwcom下载 骑嫂子 亚洲大色妣 成人故事365ahnet 丝袜家庭教mp4 幼交肛交 妹妹撸撸大妈 日本毛爽 caoprom超碰在email 关于中国古代偷窥的黄片 第一会所老熟女下载 wwwhuangsecome 狼人干综合新地址HD播放 变态儿子强奸乱伦图 强奸电影名字 2wwwer37com 日本毛片基地一亚洲AVmzddcxcn 暗黑圣经仙桃影院 37tpcocn 持月真由xfplay 好吊日在线视频三级网 我爱背入李丽珍 电影师傅床戏在线观看 96插妹妹sexsex88com 豪放家庭在线播放 桃花宝典极夜著豆瓜网 安卓系统播放神器 美美网丝袜诱惑 人人干全免费视频xulawyercn av无插件一本道 全国色五月 操逼电影小说网 good在线wwwyuyuelvcom www18avmmd 撸波波影视无插件 伊人幼女成人电影 会看射的图片 小明插看看 全裸美女扒开粉嫩b 国人自拍性交网站 萝莉白丝足交本子 七草ちとせ巨乳视频 摇摇晃晃的成人电影 兰桂坊成社人区小说www68kqcom 舔阴论坛 久撸客一撸客色国内外成人激情在线 明星门 欧美大胆嫩肉穴爽大片 www牛逼插 性吧星云 少妇性奴的屁眼 人体艺术大胆mscbaidu1imgcn 最新久久色色成人版 l女同在线 小泽玛利亚高潮图片搜索 女性裸b图 肛交bt种子 最热门有声小说 人间添春色 春色猜谜字 樱井莉亚钢管舞视频 小泽玛利亚直美6p 能用的h网 还能看的h网 bl动漫h网 开心五月激 东京热401 男色女色第四色酒色网 怎么下载黄色小说 黄色小说小栽 和谐图城 乐乐影院 色哥导航 特色导航 依依社区 爱窝窝在线 色狼谷成人 91porn 包要你射电影 色色3A丝袜 丝袜妹妹淫网 爱色导航(荐) 好男人激情影院 坏哥哥 第七色 色久久 人格分裂 急先锋 撸撸射中文网 第一会所综合社区 91影院老师机 东方成人激情 怼莪影院吹潮 老鸭窝伊人无码不卡无码一本道 av女柳晶电影 91天生爱风流作品 深爱激情小说私房婷婷网 擼奶av 567pao 里番3d一家人野外 上原在线电影 水岛津实透明丝袜 1314酒色 网旧网俺也去 0855影院 在线无码私人影院 搜索 国产自拍 神马dy888午夜伦理达达兔 农民工黄晓婷 日韩裸体黑丝御姐 屈臣氏的燕窝面膜怎么样つぼみ晶エリーの早漏チ○ポ强化合宿 老熟女人性视频 影音先锋 三上悠亚ol 妹妹影院福利片 hhhhhhhhsxo 午夜天堂热的国产 强奸剧场 全裸香蕉视频无码 亚欧伦理视频 秋霞为什么给封了 日本在线视频空天使 日韩成人aⅴ在线 日本日屌日屄导航视频 在线福利视频 日本推油无码av magnet 在线免费视频 樱井梨吮东 日本一本道在线无码DVD 日本性感诱惑美女做爱阴道流水视频 日本一级av 汤姆avtom在线视频 台湾佬中文娱乐线20 阿v播播下载 橙色影院 奴隶少女护士cg视频 汤姆在线影院无码 偷拍宾馆 业面紧急生级访问 色和尚有线 厕所偷拍一族 av女l 公交色狼优酷视频 裸体视频AV 人与兽肉肉网 董美香ol 花井美纱链接 magnet 西瓜影音 亚洲 自拍 日韩女优欧美激情偷拍自拍 亚洲成年人免费视频 荷兰免费成人电影 深喉呕吐XXⅩX 操石榴在线视频 天天色成人免费视频 314hu四虎 涩久免费视频在线观看 成人电影迅雷下载 能看见整个奶子的香蕉影院 水菜丽百度影音 gwaz079百度云 噜死你们资源站 主播走光视频合集迅雷下载 thumbzilla jappen 精品Av 古川伊织star598在线 假面女皇vip在线视频播放 国产自拍迷情校园 啪啪啪公寓漫画 日本阿AV 黄色手机电影 欧美在线Av影院 华裔电击女神91在线 亚洲欧美专区 1日本1000部免费视频 开放90后 波多野结衣 东方 影院av 页面升级紧急访问每天正常更新 4438Xchengeren 老炮色 a k福利电影 色欲影视色天天视频 高老庄aV 259LUXU-683 magnet 手机在线电影 国产区 欧美激情人人操网 国产 偷拍 直播 日韩 国内外激情在线视频网给 站长统计一本道人妻 光棍影院被封 紫竹铃取汁 ftp 狂插空姐嫩 xfplay 丈夫面前 穿靴子伪街 XXOO视频在线免费 大香蕉道久在线播放 电棒漏电嗨过头 充气娃能看下毛和洞吗 夫妻牲交 福利云点墦 yukun瑟妃 疯狂交换女友 国产自拍26页 腐女资源 百度云 日本DVD高清无码视频 偷拍,自拍AV伦理电影 A片小视频福利站。 大奶肥婆自拍偷拍图片 交配伊甸园 超碰在线视频自拍偷拍国产 小热巴91大神 rctd 045 类似于A片 超美大奶大学生美女直播被男友操 男友问 你的衣服怎么脱掉的 亚洲女与黑人群交视频一 在线黄涩 木内美保步兵番号 鸡巴插入欧美美女的b舒服 激情在线国产自拍日韩欧美 国语福利小视频在线观看 作爱小视颍 潮喷合集丝袜无码mp4 做爱的无码高清视频 牛牛精品 伊aⅤ在线观看 savk12 哥哥搞在线播放 在线电一本道影 一级谍片 250pp亚洲情艺中心,88 欧美一本道九色在线一 wwwseavbacom色av吧 cos美女在线 欧美17,18ⅹⅹⅹ视频 自拍嫩逼 小电影在线观看网站 筱田优 贼 水电工 5358x视频 日本69式视频有码 b雪福利导航 韩国女主播19tvclub在线 操逼清晰视频 丝袜美女国产视频网址导航 水菜丽颜射房间 台湾妹中文娱乐网 风吟岛视频 口交 伦理 日本熟妇色五十路免费视频 A级片互舔 川村真矢Av在线观看 亚洲日韩av 色和尚国产自拍 sea8 mp4 aV天堂2018手机在线 免费版国产偷拍a在线播放 狠狠 婷婷 丁香 小视频福利在线观看平台 思妍白衣小仙女被邻居强上 萝莉自拍有水 4484新视觉 永久发布页 977成人影视在线观看 小清新影院在线观 小鸟酱后丝后入百度云 旋风魅影四级 香蕉影院小黄片免费看 性爱直播磁力链接 小骚逼第一色影院 性交流的视频 小雪小视频bd 小视频TV禁看视频 迷奸AV在线看 nba直播 任你在干线 汤姆影院在线视频国产 624u在线播放 成人 一级a做爰片就在线看狐狸视频 小香蕉AV视频 www182、com 腿模简小育 学生做爱视频 秘密搜查官 快播 成人福利网午夜 一级黄色夫妻录像片 直接看的gav久久播放器 国产自拍400首页 sm老爹影院 谁知道隔壁老王网址在线 综合网 123西瓜影音 米奇丁香 人人澡人人漠大学生 色久悠 夜色视频你今天寂寞了吗? 菲菲影视城美国 被抄的影院 变态另类 欧美 成人 国产偷拍自拍在线小说 不用下载安装就能看的吃男人鸡巴视频 插屄视频 大贯杏里播放 wwwhhh50 233若菜奈央 伦理片天海翼秘密搜查官 大香蕉在线万色屋视频 那种漫画小说你懂的 祥仔电影合集一区 那里可以看澳门皇冠酒店a片 色自啪 亚洲aV电影天堂 谷露影院ar toupaizaixian sexbj。com 毕业生 zaixian mianfei 朝桐光视频 成人短视频在线直接观看 陈美霖 沈阳音乐学院 导航女 www26yjjcom 1大尺度视频 开平虐女视频 菅野雪松协和影视在线视频 华人play在线视频bbb 鸡吧操屄视频 多啪啪免费视频 悠草影院 金兰策划网 (969) 橘佑金短视频 国内一极刺激自拍片 日本制服番号大全magnet 成人动漫母系 电脑怎么清理内存 黄色福利1000 dy88午夜 偷拍中学生洗澡磁力链接 花椒相机福利美女视频 站长推荐磁力下载 mp4 三洞轮流插视频 玉兔miki热舞视频 夜生活小视频 爆乳人妖小视频 国内网红主播自拍福利迅雷下载 不用app的裸裸体美女操逼视频 变态SM影片在线观看 草溜影院元气吧 - 百度 - 百度 波推全套视频 国产双飞集合ftp 日本在线AV网 笔国毛片 神马影院女主播是我的邻居 影音资源 激情乱伦电影 799pao 亚洲第一色第一影院 av视频大香蕉 老梁故事汇希斯莱杰 水中人体磁力链接 下载 大香蕉黄片免费看 济南谭崔 避开屏蔽的岛a片 草破福利 要看大鸡巴操小骚逼的人的视频 黑丝少妇影音先锋 欧美巨乳熟女磁力链接 美国黄网站色大全 伦蕉在线久播 极品女厕沟 激情五月bd韩国电影 混血美女自摸和男友激情啪啪自拍诱人呻吟福利视频 人人摸人人妻做人人看 44kknn 娸娸原网 伊人欧美 恋夜影院视频列表安卓青青 57k影院 如果电话亭 avi 插爆骚女精品自拍 青青草在线免费视频1769TV 令人惹火的邻家美眉 影音先锋 真人妹子被捅动态图 男人女人做完爱视频15 表姐合租两人共处一室晚上她竟爬上了我的床 性爱教学视频 北条麻妃bd在线播放版 国产老师和师生 magnet wwwcctv1024 女神自慰 ftp 女同性恋做激情视频 欧美大胆露阴视频 欧美无码影视 好女色在线观看 后入肥臀18p 百度影视屏福利 厕所超碰视频 强奸mp magnet 欧美妹aⅴ免费线上看 2016年妞干网视频 5手机在线福利 超在线最视频 800av:cOm magnet 欧美性爱免播放器在线播放 91大款肥汤的性感美乳90后邻家美眉趴着窗台后入啪啪 秋霞日本毛片网站 cheng ren 在线视频 上原亚衣肛门无码解禁影音先锋 美脚家庭教师在线播放 尤酷伦理片 熟女性生活视频在线观看 欧美av在线播放喷潮 194avav 凤凰AV成人 - 百度 kbb9999 AV片AV在线AV无码 爱爱视频高清免费观看 黄色男女操b视频 观看 18AV清纯视频在线播放平台 成人性爱视频久久操 女性真人生殖系统双性人视频 下身插入b射精视频 明星潜规测视频 mp4 免賛a片直播绪 国内 自己 偷拍 在线 国内真实偷拍 手机在线 国产主播户外勾在线 三桥杏奈高清无码迅雷下载 2五福电影院凸凹频频 男主拿鱼打女主,高宝宝 色哥午夜影院 川村まや痴汉 草溜影院费全过程免费 淫小弟影院在线视频 laohantuiche 啪啪啪喷潮XXOO视频 青娱乐成人国产 蓝沢润 一本道 亚洲青涩中文欧美 神马影院线理论 米娅卡莉法的av 在线福利65535 欧美粉色在线 欧美性受群交视频1在线播放 极品喷奶熟妇在线播放 变态另类无码福利影院92 天津小姐被偷拍 磁力下载 台湾三级电髟全部 丝袜美腿偷拍自拍 偷拍女生性行为图 妻子的乱伦 白虎少妇 肏婶骚屄 外国大妈会阴照片 美少女操屄图片 妹妹自慰11p 操老熟女的b 361美女人体 360电影院樱桃 爱色妹妹亚洲色图 性交卖淫姿势高清图片一级 欧美一黑对二白 大色网无毛一线天 射小妹网站 寂寞穴 西西人体模特苍井空 操的大白逼吧 骚穴让我操 拉好友干女朋友3p